Longevity & Brain Health
Clinical Intelligence Hub • Expert Curation
Preserving cognitive function and neurovascular integrity is essential for long-term healthspan. We analyze publications exploring cellular neuroprotection, synaptic density, and biological interventions that support mental stamina, memory preservation, and brain age deceleration.
A primate study on HMGB1 gene therapy reveals how resetting key aging biomarkers like APOE and SHBG could help manage age-related biological decline.
Discover how the novel combinatorial drug SRN-901 targets multiple biological aging pathways to extend lifespan and reduce physical frailty in mouse models.
A landmark clinical trial reveals that rapamycin side effects may include the unexpected blunting of physical strength and exercise gains in older adults.
A mindfulness-based cognitive therapy clinical trial maps brain dynamics, showing how structured meditation breaks rigid loops of depressive rumination.
Explore how cryptic transcription in aging creates cellular noise, and how new genetic tools and epigenetic diagnostics help restore cellular health.
Discover how physical frailty and cognitive decline are closely linked in older adults, and learn the key modifiable risk factors to preserve autonomy.
New brain atrophy mapping research identifies four distinct progression subtypes in Lewy body diseases, offering a predictive path for cognitive preservation.
RetiBrain, a novel AI cross-modal deep learning framework, predicts critical neuroimaging biomarkers of brain health from simple retinal color fundus photography.
Deep learning model RetiBrain predicts brain health biomarkers from retinal scans to enable early disease screenings.